The Vitamin B12 and Folate Test measures the level of vitamin B12 and folate in your blood. Vitamin B12 and folate are essential nutrients that are necessary for producing and maintaining red and white blood cells, supporting the nervous system, and helping to create DNA, the basis of all cells.
Vitamin B12 and folate must be supplied by the diet or through supplementation because the body is not able to produce them. Vitamin B12 and folate deficiency (low levels of vitamin B12 or folate) may be due to limited dietary intake, poor absorption, advanced age, certain medical conditions, or some medications. Low levels of vitamin B12 and folate can lead to anemia, nervous system conditions, and a variety of health issues. This test can help determine whether you have a vitamin B12 or folate deficiency.
What is tested?
The Vitamin B12 and Folate Test measures the level of vitamin B12 and folate in your blood.
Vitamin B12
Vitamin B12 is absorbed in the small intestine and then makes its way to the blood and cells. The body also stores vitamin B12 in the liver for future use. Vitamin B12 is essential in supporting the nervous system, making red blood cells, and creating DNA (the genetic material present in our cells). Vitamin B12 must be supplied by the diet or supplementation because the body is not able to produce it independently. It is naturally found in animal proteins, such as red meat, fish, poultry, eggs, and dairy. Plant foods have no vitamin B12 unless they are fortified.
Low levels of vitamin B12 may occur if you do not consume enough vitamin B12 or the body does not store or absorb enough of the vitamin. People who are deficient in vitamin B12 may or may not have any symptoms of anemia (a condition in which your body does not have enough healthy red cells to carry oxygen to your body’s tissues) or nerve damage. Early detection is important to prevent irreversible damage over time, especially to the nervous system.
Folate
Folate, also known as vitamin B9, is necessary for red and white blood cell development; tissue growth; cell function; the breakdown, usage, and creation of proteins; and the production of DNA. This vitamin is essential during pregnancy to help prevent birth defects and congenital disabilities of the brain (anencephaly) and spine (spina bifida). Folate enables the proper growth of fetal tissues and cells. Folate must be supplied by the diet or through supplementation because the body is not able to produce it independently. Folate is naturally found in beans and peas, citrus fruits, leafy green vegetables, and yeast. Folic acid is the manufactured (synthetic) version of folate, which is found in supplements and fortified foods.
Low levels of folate may occur if people do not consume enough folate or the body does not store or absorb enough of the vitamin. People who are deficient in folate may not have any symptoms or may present with symptoms of anemia (a condition in which your body does not have enough healthy red cells to carry oxygen to your body’s tissues) or nerve damage. Early detection is important to prevent irreversible damage over time, especially to the nervous system.
Signs & Symptoms
People with low levels of vitamin B12 or folate may not have any symptoms or may have symptoms of anemia or nerve damage. General symptoms related to anemia and nerve damage include fatigue, weakness, difficulty concentrating, depression, numbness or tingling in the hands and feet, headaches, moodiness, and gastrointestinal symptoms. Some people may not have all or any of these symptoms but still have a deficiency.
You may consider a Vitamin B12 and Folate Test if you are experiencing the following symptoms:
If you are experiencing severe symptoms, such as abnormal heartbeat, heart flutters, fainting, shortness of breath, extreme fatigue, unsteady gait, or severe bruising, or if you are experiencing infertility issues, speak with your healthcare provider before purchasing this test.
Eligibility
The Vitamin B12 and Folate Panel is for anyone who wants to monitor their vitamin B12 and folate levels. You must be 18 years of age or older to purchase.
Preparing For Your Test
Dietary supplements containing biotin may interfere with this panel, causing results to be either falsely high or falsely low. We recommend pausing biotin-containing supplements 72 hours prior to being tested. This panel does not require fasting.
After The Test
When your results are ready, we will send them to you in a clear, easy-to-read report. You will have the option to speak with an independent physician to discuss your results. If your results differ from the expected ranges, you may receive an alert call to inform you.
